“Chronic Fatigue System (CFS) is a biological disease not a psychological one” – Researchers confirmsMd Noman Siddique (Author) Published Date : Mar 01, 2015 09:53 IST
It is evident from research conducted by scientists that chronic fatigue syndrome or CFS is the result of immunological dysfunction. This makes it clear that this is a biological disease, even though previously it was widely considered a psychological disorder.
A person with CFS or systematic exertion intolerance disease goes through a severe fatigue and a very hard time to concentrate on things since this illness comes with a package of headaches and muscle pain.
Mady Hornig, the lead author of the study, director of translational research at the Centre for Infection and Immunity, Columbia University has stated that We now have evidence confirming what millions of people with this disease already know, that CFS is not psychological.
She further included Our results should accelerate the process of establishing the diagnosis after individuals first fall ill as well as discovery of new treatment strategies focusing on these early blood markers.
While conducting this study, the researchers came to indentify distinctive changes in immunity in patients who were diagnosed with CFS or ME which refers to myalgic encephalomyelitis, another medical term for chronic fatigue syndrome.
The researchers have applied immunoassay testing methods for determining the levels of 51 immune biomarkers in blood plasma samples. These samples were accumulated with the assistance of 2 multicentre studies representing a total of 298 myalgic encephalomyelitis or chronic fatigue syndrome patients and 348 healthy controls.
Researchers discovered unambiguous patterns in sufferers who suffered the illness for about 3 years or less than that and were not part of the healthy controls or suffers who has been experiencing this disease for more than 3 years or so.
It was identified that patients with a small duration had augmented amount of various kinds of immune molecules referred to as cytokines .
This connection was oddly strong with a particular cytokine known as interferon gamma which has been associated to the fatigue which is followed by numerous viral infections.
The study was published in the journal called Science Advances and according to the senior author W. Ian Lipkin from Columbia University's Mailman School of Public Health This study delivers what has eluded us for so long: unequivocal evidence of immunological dysfunction in ME/CFS and diagnostic biomarkers for disease.
“Chronic Fatigue System (CFS) is a biological disease not a psychological one” – Researchers confirms